Olive oil contains oleuropein, a potent antioxidant compound, for which previous researchers have identified the capacity to inhibit cell proliferation of breast and urinary cancers, as well, as to decrease breast cancer cell viability.?? ZK Hassan, from King Saud University (Saudi Arabia), and colleagues investigated the effect of oleuropein on the metastatic and anti-metastatic gene expression in the MDA human breast cancer cell line. The team observed that oleuropein initially down-regulated matrix Metalloproteinase (MMP) genes ? thought to be overexpressed in tumor cells; and oleuropein promoted the tissue inhibitors of metalloproteinases (TIMPS) ? with which cell-death inducing properties are associated. The study authors submit that: ?oleuropein plays an important role in regulating MDA cell metastasis by suppressing the expression of MMP-2 and MMP-9 genes and upregulating the expression of TIMP1 and TIMP4 genes in breast cancer cells therefore it can help in tailoring new anti-metastatic cancer therapy.?
Hassan ZK, Elamin MH, Daghestani MH, Omer SA, Al-Olayan EM, Elobeid MA, Virk P, Mohammed OB. ?Oleuropein Induces Anti-metastatic Effects in Breast Cancer.? Asian Pac J Cancer Prev. 2012;13(9):4555-9.
Health Headlines MORE ?
Vitamin D may help to battle cancers, by blocking cell growth and slowing the progression of pre-malignant tumors to malignancy.
Living in areas of high air pollution can lead to decreased cognitive function in older adults.
Oleuropein, the main polyphenol compound present in olive oil, induces anti-metastatic effects on human breast cancer cell lines.
Review confirms the value of omega-3 fatty acids in reducing the risk of heart disease.
Mental activities like reading and writing can preserve structural integrity in the brain, as people age.
When estimating cardiovascular disease risk, Swiss team reports that body mass index (BMI) is a more accurate predictor than cholesterol levels.
Optimal heart health in middle age helps the odds of living up to 14 years longer, free of cardiovascular disease.
Epigallocatechin gallate, an antioxidant compound found abundantly in green tea, helps to reduce blood sugar spikes after starchy meals, in a lab animal model.
Individuals with telomeres in the shortest 10% may be 23% more likely to die in the three years following measurement of these DNA endcaps.
The antibiotic-resistant ?superbug? methicillin-resistant Staphylococcus aureus (MRSA) is prevalent at several US wastewater treatment plants.
Source: http://www.worldhealth.net/news/olive-oil-compound-exerts-anti-cancer-effects/
metta world peace ron artest gladys knight private practice deion sanders creutzfeldt jakob disease the lone ranger
No comments:
Post a Comment